[modeller_usage] normalized DOPE - expected values vs quality of template?
To:
Subject: [modeller_usage] normalized DOPE - expected values vs quality of template?
From: Daniel Rigden <>
Date: Thu, 20 Nov 2008 10:02:42 +0000
Dear all
I expect this is more a question for the developers, but perhaps other
users have relevant experiences to share.
With 9v5 we have the very useful Z scores from a normalized DOPE
assessment. The manual says that +ve scores are bad, and that anything
less than -1 or so is 'native-like'. Presumably the best achievable Z
score will depend very much on the available templates - we should be
able to do much better with 70% identical templates than with 30%
identical templates. Has anyone got a feel for what kind of figures we
should be happy with (and be able to quote in a paper as supporting the
quality of our model) in different ranges of template % sequence
identity?
Thanks in advance
Dan
--
Dr Daniel John Rigden Tel:(+44) 151 795 4467
School of Biological Sciences FAX:(+44) 151 795 4406
Room 101, Biosciences Building
University of Liverpool
Crown St.,
Liverpool L69 7ZB, U.K.