assess multiple chain modelling

Hello, I have successfully modelled a population of tetramers. But I would like to assess them. I found that the DOPE and the GA341 scores are not suitable to assess multiple chain proteins. So, which scoring scheme can I use ? Thanks in advance. Dimitri ---------------------------------------------------------------------------------------- Dimitri Gilis Genomic and Structural Bioinformatics 3BIO - Service de Biosystèmes, Biomodélisation et Bioprocédés (Biosystems, Biomodelling and Bioprocess Department) Université Libre de Bruxelles Av. F. Roosevelt, 50 CP 165/61 1050 Brussels Belgium Tel: +32 2 650 36 15 Fax: +32 2 650 35 75 e-mail: dgilis@ulb.ac.be

On 2/9/11 4:41 AM, Dimitri Gilis wrote: > I have successfully modelled a population of tetramers. But I would like > to assess them. I found that the DOPE and the GA341 scores are not > suitable to assess multiple chain proteins. So, which scoring scheme can > I use ? You can certainly use DOPE and GA341, but should be aware that because only single-chain proteins were used in their construction, inter-chain interactions may not be correctly scored. Ben Webb, Modeller Caretaker -- modeller-care@salilab.org http://www.salilab.org/modeller/ Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage
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Dimitri Gilis
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Modeller Caretaker