Best practices in point mutation
I've noticed Sali and Fiser have a 2007 article on point mutations (Modeling mutations in protein structures, Protein Science 16:2030-2041). I couldn't find the modeller script for that protocol, though. Is it available somewhere? Would the protocol at the wiki ( http://salilab.org/modeller/wiki/Mutate%20model ) be the most reliable approach these days?
Cheers, Lucas
On 7/26/16 12:56 PM, Lucas wrote: > I've noticed Sali and Fiser have a 2007 article on point mutations > (Modeling mutations in protein structures, Protein Science > 16:2030-2041). I couldn't find the modeller script for that protocol, > though. Is it available somewhere? Would the protocol at the wiki ( > http://salilab.org/modeller/wiki/Mutate%20model ) be the most reliable > approach these days?
Yes, that script implements the same protocol they used, with modern Modeller.
Ben Webb, Modeller Caretaker
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Modeller Caretaker