remodelling a fragment of protein using different template.
greetings readers,
I am trying to model a protein with low homology. I have used ab initio methods to get a starting structure. but i want to remodel first 50-100 residues according to a different PDB template. is it possible to do so using modeller? please give some suggestions
*Yogesh Sharma*
On 2/15/21 9:11 AM, Yogesh Sharma wrote: > I am trying to model a protein with low homology. I have used ab > initio methods to get a starting structure. but i want to remodel first > 50-100 residues according to a different PDB template. is it possible to > do so using modeller?
Sure, just model using two templates, one for the first 50-100 residues and your ab initio model for the rest. See https://salilab.org/modeller/FAQ.html#1
Ben Webb, Modeller Caretaker
participants (2)
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Modeller Caretaker -
Yogesh Sharma