Hi! I am looking for a simple method to score a model from Modeller directly against raw experimental cristallography data. The idea is to use models from Modeller for molecular replacement in borderline situations - that is in situations where the standard cristallographers molecular replacement tools fail. Thus, the method should be automatic and not require hand-tuning, so that I can generate lots of different models (e.g. based on different loop refinement parameters) until I find one that does the trick. Do you know about someone who already tried this. Thank you very much, kind regards, Karsten. -- Karsten Suhre Information Genetique & Structurale UMR CNRS 1889 31, chemin Joseph Aiguier F-13402 Marseille Cedex 20 mailto:Karsten.Suhre@igs.cnrs-mrs.fr http://igs-server.cnrs-mrs.fr/~suhre