Archana Chavan wrote: > can anybody suggest me anything about my problem? > i am trying to model the structure of an oxidoreductase enzyme, for > which thetemplate is of lenth shorter than the query sequence. > last 47 amino acid residues at c-terminus of the protein didnot match > wiht any template structure, and there are chances of these residues to > be involved in formation of active site. so is there any method by which > i can model this lenght of residues without alignment with any 3d > structure? If you don't have a template, then you are unlikely to be able to get a high quality model, since you essentially have to solve the protein folding problem. Ben Webb, Modeller Caretaker -- modeller-care@salilab.org http://www.salilab.org/modeller/ Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage