Re: [modeller_usage] remodelling a fragment of protein using different template.

On 2/15/21 9:11 AM, Yogesh Sharma wrote: >  I am trying to model a protein with low homology. I have used ab > initio methods to get a starting structure. but i want to remodel first > 50-100 residues according to a different PDB template. is it possible to > do so using modeller?

Sure, just model using two templates, one for the first 50-100 residues and your ab initio model for the rest. See https://salilab.org/modeller/FAQ.html#1

Ben Webb, Modeller Caretaker