Dear Modeller users, I constructed a model of a protein using a template which contains only the Calpha trace. Due to a question of a reviewer of the article i submitted for publication, i am seeking for precisions on how the Calpha trace is rebuilt to atomic resolution and then made into the model. I guess these steps are performed by the functions: model.generate_topology() and/or Restraints.make(), but i do not understand how modeller generates all the essential restraints to build the model when almost all the atoms of the template are missing except the Calpha. Does these restraints come from a library ? In this case, how is this library built ? I did not mange to find many details concerning this point in the manual, so i would really appreciate if anyone could give me some explanations. Many thanks in advance for your time and knowledge. JPB -- Jean-Paul BECKER Structure et Fonction des Membranes Biologiques (SFMB) Centre de Biologie Structurale et de Bioinformatique (CBSB) Faculté des Sciences Université Libre de Bruxelles Campus de la Plaine CP 206/2 Boulevard du Triomphe 1050 BRUXELLES BELGIQUE