[modeller_usage] Re: Design of a chmieric protein from two known structures

[Joel Subach <mjsubach AT alumni.ncsu.edu>]

Hi I would try multiple and a single template approach, thanks:)

On Wed, Mar 15, 2023 at 1:49 PM dafnikarr--- via modeller_usage <
modeller_usage@listsrv.ucsf.edu> wrote:

> Hello ,
> i want to design a chimeric protein by fusion of subdomains of two known
> proteins. Do you know how should write the relevant scripts? And how to do
> the alignment? Should i use the multi template approach and use the two
> proteins as a template?
> Thank you!
> Dafni
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Hi I would try multiple and a single template approach, thanks:)

On Wed, Mar 15, 2023 at 1:49â?¯PM dafnikarr--- via modeller_usage <modeller_usage@listsrv.ucsf.edu> wrote:

Hello ,
i want to design a chimeric protein by fusion of subdomains of two known proteins. Do you know how should write the relevant scripts? And how to do the alignment? Should i use the multi template approach and use the two proteins as a template?
Thank you!
Dafni
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