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problem with files .top



(- suse linux 8.1
 - modeller6v2
 - file pdb is pdb1f4a.ent
)


with file modelo1.top the process to run correctly
 

INCLUDE

SET OUTPUT_CONTROL = 1 1 1 1 1
SET ALNFILE  = 'archivo.ali'
SET KNOWNS   = '1f4aC'
SET SEQUENCE = 'sec1'
SET STARTING_MODEL= 1
SET ENDING_MODEL  = 1

CALL ROUTINE = 'model'

-----------------------------------------------------------------------------------------------------
BUT

with file modelo2.top the process  not run

INCLUDE

SET OUTPUT_CONTROL = 1 1 1 1 1
SET ALNFILE  = 'archivo.ali'
SET KNOWNS   = '1f4aC'
SET SEQUENCE = 'sec1'
SET STARTING_MODEL= 1
SET ENDING_MODEL  = 1

CALL ROUTINE = 'model'

and log file is:

                         MODELLER 6v2, 17 Feb 2002

     PROTEIN STRUCTURE MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS

                                                                
                     Copyright(c) 1989-2002 Andrej Sali         
                            All Rights Reserved                 
                                                                
                            Written by A. Sali                  
          with help from A. Fiser, R. Sanchez, M.A. Marti-Renom,
                   B. Jerkovic, A. Badretdinov, F. Melo,        
                       J.P. Overington & E. Feyfant             
                   Rockefeller University, New York, USA        
                     Harvard University, Cambridge, USA         
                 Imperial Cancer Research Fund, London, UK      
             Birkbeck College, University of London, London, UK 


Kind, OS, HostName, Kernel, Processor: 4, Linux bioinf4 2.4.19-4GB i686
Date and time of compilation         : 07/16/2002 11:42:16
Job starting time (YY/MM/DD HH:MM:SS): 2003/04/23  11:53:47.784

TOP_________>   105  705 SET ALNFILE  = 'archivo.ali'
 
TOP_________>   106  706 SET KNOWNS   = '1f4aC'
 
TOP_________>   107  707 SET SEQUENCE = 'sec1'
 
TOP_________>   108  708 SET STARTING_MODEL = 1
 
TOP_________>   109  709 SET ENDING_MODEL  = 1
 

Dynamically allocated memory at          finish [B,kB,MB]:      2200483    2148.909     2.099
Starting time                                            : 2003/04/23  11:53:47.784
Closing time                                             : 2003/04/23  11:53:50.734
Total CPU time [seconds]                                 :       2.88

----------------------------------------------------------------------------------------
which is a problem?

which is a difference between the files modelo1.top and modelo2.top?

is a bug the modeller?

the files top to contain the same information but with file model2.top the process not run.


thanks..







INCLUDE

SET OUTPUT_CONTROL = 1 1 1 1 1
SET ALNFILE  = 'archivo.ali'
SET KNOWNS   = '1f4aC'
SET SEQUENCE = 'sec1'
SET STARTING_MODEL= 1
SET ENDING_MODEL  = 1

CALL ROUTINE = 'model'
INCLUDE

SET OUTPUT_CONTROL = 1 1 1 1 1
SET ALNFILE  = 'archivo.ali'
SET KNOWNS   = '1f4aC'
SET SEQUENCE = 'sec1'
SET STARTING_MODEL= 1
SET ENDING_MODEL  = 1

CALL ROUTINE = 'model'
                         MODELLER 6v2, 17 Feb 2002

     PROTEIN STRUCTURE MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS

                                                                 
                     Copyright(c) 1989-2002 Andrej Sali          
                            All Rights Reserved                  
                                                                 
                            Written by A. Sali                   
          with help from A. Fiser, R. Sanchez, M.A. Marti-Renom, 
                   B. Jerkovic, A. Badretdinov, F. Melo,         
                       J.P. Overington & E. Feyfant              
                   Rockefeller University, New York, USA         
                     Harvard University, Cambridge, USA          
                 Imperial Cancer Research Fund, London, UK       
             Birkbeck College, University of London, London, UK  


Kind, OS, HostName, Kernel, Processor: 4, Linux bioinf4 2.4.19-4GB i686
Date and time of compilation         : 07/16/2002 11:42:16
Job starting time (YY/MM/DD HH:MM:SS): 2003/04/23  11:53:47.784

TOP_________>   105  705 SET ALNFILE  = 'archivo.ali' 
 
TOP_________>   106  706 SET KNOWNS   = '1f4aC' 
 
TOP_________>   107  707 SET SEQUENCE = 'sec1' 
 
TOP_________>   108  708 SET STARTING_MODEL = 1 
 
TOP_________>   109  709 SET ENDING_MODEL  = 1 
 

Dynamically allocated memory at          finish [B,kB,MB]:      2200483    2148.909     2.099
Starting time                                            : 2003/04/23  11:53:47.784
Closing time                                             : 2003/04/23  11:53:50.734
Total CPU time [seconds]                                 :       2.88
                         MODELLER 6v2, 17 Feb 2002

     PROTEIN STRUCTURE MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS

                                                                 
                     Copyright(c) 1989-2002 Andrej Sali          
                            All Rights Reserved                  
                                                                 
                            Written by A. Sali                   
          with help from A. Fiser, R. Sanchez, M.A. Marti-Renom, 
                   B. Jerkovic, A. Badretdinov, F. Melo,         
                       J.P. Overington & E. Feyfant              
                   Rockefeller University, New York, USA         
                     Harvard University, Cambridge, USA          
                 Imperial Cancer Research Fund, London, UK       
             Birkbeck College, University of London, London, UK  


Kind, OS, HostName, Kernel, Processor: 4, Linux bioinf4 2.4.19-4GB i686
Date and time of compilation         : 07/16/2002 11:42:16
Job starting time (YY/MM/DD HH:MM:SS): 2003/04/23  11:48:58.409

TOP_________>   105  705 SET ALNFILE  = 'archivo.ali' 
 
TOP_________>   106  706 SET KNOWNS   = '1f4aC' 
 
TOP_________>   107  707 SET SEQUENCE = 'sec1' 
 
TOP_________>   108  708 SET STARTING_MODEL = 1 
 
TOP_________>   109  709 SET ENDING_MODEL  = 1 
 
TOP_________>   110  710 CALL ROUTINE = 'model' 
 
TOP_________>   111  399 CALL ROUTINE = 'getnames' 
 
TOP_________>   112  509 STRING_IF STRING_ARGUMENTS = MODEL 'undefined', OPERATION;
                       = 'EQ', THEN =     'STRING_OPERATE OPERATION = CONCATENA;
                      TE, STRING_ARGUMENTS = SEQUENCE .ini, RESULT = MODEL' 
 
TOP_________>   113  510 STRING_IF STRING_ARGUMENTS = CSRFILE 'undefined', OPERATI;
                      ON = 'EQ', THEN =     'STRING_OPERATE OPERATION = CONCATE;
                      NATE, STRING_ARGUMENTS = SEQUENCE .rsr,  RESULT = CSRFILE;
                      ' 
 
TOP_________>   114  511 STRING_OPERATE OPERATION = 'CONCATENATE',                ;
                         STRING_ARGUMENTS = SEQUENCE '.sch',  RESULT = SCHFILE 
 
TOP_________>   115  512 STRING_OPERATE OPERATION = 'CONCATENATE',                ;
                        STRING_ARGUMENTS = SEQUENCE '.mat',  RESULT = MATRIX_FI;
                      LE 
 
TOP_________>   116  513 SET ROOT_NAME = SEQUENCE 
 
TOP_________>   117  514 RETURN 
 
TOP_________>   118  400 CALL ROUTINE = 'homcsr' 
 
TOP_________>   119  106 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS SEQUE;
                      NCE 
 

Dynamically allocated memory at         amaxseq [B,kB,MB]:      2205269    2153.583     2.103
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Dynamically allocated memory at         amaxbnd [B,kB,MB]:      3908769    3817.157     3.728
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
  2       sec1     108      1        sec1 
TOP_________>   120  107 CHECK_ALIGNMENT 
 
check_a_343_> >> BEGINNING OF COMMAND
openf5__224_> Open       11  OLD  SEQUENTIAL  ./pdb1f4a.ent

check_ali___> Checking the sequence-structure alignment. 

Implied target CA(i)-CA(i+1) distances longer than  8.0 angstroms:

ALN_POS  TMPL  RID1  RID2  NAM1  NAM2     DIST
----------------------------------------------
END OF TABLE
check_a_344_> << END OF COMMAND
TOP_________>   121  108 CALL ROUTINE = GENERATE_METHOD 
 
TOP_________>   122   77 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Dynamically allocated memory at         amaxseq [B,kB,MB]:      3799237    3710.192     3.623
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
TOP_________>   123   78 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
TOP_________>   124   79 IF ARGUMENTS = INITIAL_MALIGN3D 0, OPERATION = 'EQ', THEN;
                       = 'GO_TO NO_INITIAL_MALIGN3D' 
 
TOP_________>   125   82 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS SEQUE;
                      NCE 
 

Dynamically allocated memory at         amaxseq [B,kB,MB]:      3908769    3817.157     3.728
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
  2       sec1     108      1        sec1 
TOP_________>   126   83 READ_TOPOLOGY   FILE = TOPLIB 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib//top_heav.lib
openf5__224_> Open       11  UNKNOWN  SEQUENTIAL  ${MODINSTALL6v2}/modlib/models.lib
TOP_________>   127   84 READ_PARAMETERS FILE = PARLIB 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib//par.lib

Dynamically allocated memory at       amattacns [B,kB,MB]:      3909165    3817.544     3.728
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib//par.lib
rdparf__232_> parameters    BONDS   ANGLS  DIHEDS IMPROPS    MRFP    MODE
                              227     561     661     112       0       0
TOP_________>   128   85 CALL ROUTINE = 'create_topology' 
 
TOP_________>   129  100 GENERATE_TOPOLOGY ADD_SEQUENCE = OFF 
 

getf_______W> RTF restraint not found in the atoms list:
              residue type, indices:    12   108
              atom names           : C     +N   
              atom indices         :   878     0

getf_______W> RTF restraint not found in the atoms list:
              residue type, indices:    12   108
              atom names           : C     CA    +N    O    
              atom indices         :   878   873     0   879

mkilst______> segment topology constructed from sequence and RTF:
              segments residues atoms bonds angles dihedrals impropers:
                     1      108   879   910      0         0       396
 
patch_______> segment topology patched using RTF:     1  ;  LYS  ;  NTER
              segments residues atoms bonds angles dihedrals impropers:
                     1      108   879   910   1249      1506       396
 
iatmcls_286W> MODEL atom not classified:  ASN:OT1  ASN
iatmcls_286W> MODEL atom not classified:  ASN:OT2  ASN
patch_______> segment topology patched using RTF:   108  ;  ASN  ;  CTER
              segments residues atoms bonds angles dihedrals impropers:
                     1      108   880   911   1251      1508       397

genseg______> segment topology constructed from sequence and RTF:
              segments residues atoms bonds angles dihedrals impropers:
                     1      108   880   911   1251      1508       397
TOP_________>   130  101 CALL ROUTINE = 'default_patches' 
 
TOP_________>   131  504 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS SEQUE;
                      NCE 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
  2       sec1     108      1        sec1 
TOP_________>   132  505 PATCH_SS_TEMPLATES 
 
TOP_________>   133  506 RETURN 
 
TOP_________>   134  102 CALL ROUTINE = 'special_patches' 
 
TOP_________>   135  501 RETURN 
 
TOP_________>   136  103 RETURN 
 
TOP_________>   137   86 TRANSFER_XYZ CLUSTER_CUT = -1.0 
 
transfe_506_> MODEL is an average of all templates.
transfe_511_> Number of templates for coordinate transfer:        1
              After transfering coordinates of the equivalent template atoms,
              there are defined, undefined atoms in MODEL:      843       37
TOP_________>   138   87 BUILD_MODEL INITIALIZE_XYZ = OFF 
 
TOP_________>   139   88 WRITE_MODEL FILE = MODEL 
 
openf5__224_> Open       14  UNKNOWN  SEQUENTIAL  sec1.ini
wrpdb2__568_> Residues, atoms, selected atoms:      108      880      880
TOP_________>   140   89 RETURN 
 
TOP_________>   141  109 IF ARGUMENTS = EXIT_STAGE 2, OPERATION = 'EQ', THEN = 'RE;
                      TURN' 
 
TOP_________>   142  110 IF ARGUMENTS = CREATE_RESTRAINTS 0, OPERATION = 'EQ', THE;
                      N ='GO_TO __SKIP_RSRS' 
 
TOP_________>   143  111 CALL ROUTINE = 'mkhomcsr' 
 
TOP_________>   144  116 MAKE_RESTRAINTS RESTRAINT_TYPE = 'stereo', ADD_RESTRAINTS;
                       = OFF 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  stereo
r_stere_606_> Stereochemical restraints were constructed from RTF & PRMF.
              Added bond,angle,dihedral,improper restraints  :      911    1251    1472     387
              Total number of restraints before, now         :        0     4021
make_re_422_> Number of previous, current restraints         :        0     4021
make_re_423_> Number of previous, current selected restraints:        0     4021
TOP_________>   145  117 READ_ALIGNMENT FILE = ALNFILE, ALIGN_CODES = KNOWNS SEQUE;
                      NCE 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali
openf5__224_> Open       11  OLD  SEQUENTIAL  archivo.ali

Read the alignment from file       : archivo.ali
Total number of alignment positions:   108

  #  Code        #_Res #_Segm PDB_code    Name
-------------------------------------------------------------------------------
  1      1f4aC     108      1        1f4a 
  2       sec1     108      1        sec1 
TOP_________>   146  118 MAKE_RESTRAINTS RESTRAINT_TYPE = 'phi-psi_binormal', ADD_;
                      RESTRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  phi-psi_binormal
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mnch1.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mnch1.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
make_re_422_> Number of previous, current restraints         :     4021     4127
make_re_423_> Number of previous, current selected restraints:     4021     4127
TOP_________>   147  119 SET SPLINE_RANGE = 4.0, SPLINE_DX = 0.3, SPLINE_MIN_POINT;
                      S = 5 
 
TOP_________>   148  120 MAKE_RESTRAINTS RESTRAINT_TYPE = 'omega_dihedral', ADD_RE;
                      STRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  omega_dihedral
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/omega.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/omega.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
omgdel__425W> Unselected all O C +N +CA dihedrals:      117
make_re_422_> Number of previous, current restraints         :     4127     4234
make_re_423_> Number of previous, current selected restraints:     4127     4117
TOP_________>   149  121 MAKE_RESTRAINTS RESTRAINT_TYPE = 'chi1_dihedral', ADD_RES;
                      TRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  chi1_dihedral
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi1234.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi1.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
make_re_422_> Number of previous, current restraints         :     4234     4328
make_re_423_> Number of previous, current selected restraints:     4117     4211
TOP_________>   150  122 MAKE_RESTRAINTS RESTRAINT_TYPE = 'chi2_dihedral', ADD_RES;
                      TRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  chi2_dihedral
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi1234.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi2.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
make_re_422_> Number of previous, current restraints         :     4328     4400
make_re_423_> Number of previous, current selected restraints:     4211     4283
TOP_________>   151  123 MAKE_RESTRAINTS RESTRAINT_TYPE = 'chi3_dihedral', ADD_RES;
                      TRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  chi3_dihedral
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi1234.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi3.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
make_re_422_> Number of previous, current restraints         :     4400     4431
make_re_423_> Number of previous, current selected restraints:     4283     4314
TOP_________>   152  124 MAKE_RESTRAINTS RESTRAINT_TYPE = 'chi4_dihedral', ADD_RES;
                      TRAINTS = ON 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  chi4_dihedral
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/mdt.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi1234.bin
initmdt_400_> Distance function type:        1
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/chi4.mdt
irddata_401_> USER SYMMETRY, SYMMETRY:        1  T
              SYMMETRIC = .T. ==> NALN*NALN/2
              SYMMETRIC = .F. ==> NALN*NALN
              All protein pairs always generated.
mdtrsr__446W> A potential that relies on one protein is used, yet you have at
              least one known structure available. MDT, not library, potential is used.
getdata_643_> Protein accepted:  1f4aC
getdata_289_> Proteins (all/accepted):        1        1
make_re_422_> Number of previous, current restraints         :     4431     4441
make_re_423_> Number of previous, current selected restraints:     4314     4324
TOP_________>   153  125 SET SPLINE_RANGE = 4.0, SPLINE_DX = 0.7, SPLINE_MIN_POINT;
                      S = 5 
 
TOP_________>   154  126 SET RES_TYPES = 'STD' 
 
TOP_________>   155  127 SET DISTANCE_RSR_MODEL = 5, MAXIMAL_DISTANCE = MAX_CA-CA_;
                      DISTANCE 
 
TOP_________>   156  128 SET RESIDUE_SPAN_RANGE = 2 99999, RESIDUE_SPAN_SIGN = ON 
 
TOP_________>   157  129 SET RESTRAINT_GROUP = 9 
 
TOP_________>   158  130 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'CA' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : CA
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      108


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   159  131 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'CA' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : CA
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      108


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   160  132 MAKE_RESTRAINTS RESTRAINT_TYPE = 'distance', ADD_RESTRAIN;
                      TS = 'ON' 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     4441     5369
make_re_423_> Number of previous, current selected restraints:     4324     5252
TOP_________>   161  133 SET DISTANCE_RSR_MODEL = 6, MAXIMAL_DISTANCE = MAX_N-O_DI;
                      STANCE 
 
TOP_________>   162  134 SET RESIDUE_SPAN_RANGE = 2 99999, RESIDUE_SPAN_SIGN = OFF 
 
TOP_________>   163  135 SET RESTRAINT_GROUP = 10 
 
TOP_________>   164  136 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'N' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : N
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      108


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   165  137 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'O' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : O
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      108


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   166  138 MAKE_RESTRAINTS RESTRAINT_TYPE = 'distance', ADD_RESTRAIN;
                      TS = 'ON' 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     5369     6479
make_re_423_> Number of previous, current selected restraints:     5252     6362
TOP_________>   167  139 SET DISTANCE_RSR_MODEL = 6, MAXIMAL_DISTANCE = MAX_SC-MC_;
                      DISTANCE 
 
TOP_________>   168  140 SET RESIDUE_SPAN_RANGE = 1 2, RESIDUE_SPAN_SIGN = OFF 
 
TOP_________>   169  141 SET RESTRAINT_GROUP = 23, RESTRAINT_STDEV = 0.5 1.5 
 
TOP_________>   170  142 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'SDCH' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : SDCH
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      447


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---    7 :  VAL       7
      2    9 :  LEU  ---   17 :  LEU       9
      3   19 :  LEU  ---   39 :  LYS      21
      4   41 :  ARG  ---   53 :  ASN      13
      5   55 :  GLU  ---   91 :  HSD      37
      6   93 :  TYR  ---  108 :  ASN      16


TOP_________>   171  143 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'MNCH' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : MNCH
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      433


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   172  144 MAKE_RESTRAINTS RESTRAINT_TYPE = 'distance', ADD_RESTRAIN;
                      TS = 'ON' 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     6479     8525
make_re_423_> Number of previous, current selected restraints:     6362     8408
TOP_________>   173  145 SET DISTANCE_RSR_MODEL = 6, MAXIMAL_DISTANCE = MAX_SC-SC_;
                      DISTANCE 
 
TOP_________>   174  146 SET RESIDUE_SPAN_RANGE = 2 99999, RESIDUE_SPAN_SIGN = ON 
 
TOP_________>   175  147 SET RESTRAINT_GROUP = 26, RESTRAINT_STDEV = 0.5 2.0 
 
TOP_________>   176  148 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'SDCH' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : SDCH
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      447


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---    7 :  VAL       7
      2    9 :  LEU  ---   17 :  LEU       9
      3   19 :  LEU  ---   39 :  LYS      21
      4   41 :  ARG  ---   53 :  ASN      13
      5   55 :  GLU  ---   91 :  HSD      37
      6   93 :  TYR  ---  108 :  ASN      16


TOP_________>   177  149 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'SDCH' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : SDCH
Residue types to be searched for (RES_TYPES)   : STD
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      447


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---    7 :  VAL       7
      2    9 :  LEU  ---   17 :  LEU       9
      3   19 :  LEU  ---   39 :  LYS      21
      4   41 :  ARG  ---   53 :  ASN      13
      5   55 :  GLU  ---   91 :  HSD      37
      6   93 :  TYR  ---  108 :  ASN      16


TOP_________>   178  150 MAKE_RESTRAINTS RESTRAINT_TYPE = 'distance', ADD_RESTRAIN;
                      TS = 'ON' 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     8525     9158
make_re_423_> Number of previous, current selected restraints:     8408     9041
TOP_________>   179  151 CALL ROUTINE = 'hetatm_restraints' 
 
TOP_________>   180  160 SET RESTRAINT_TYPE = 'distance' 
 
TOP_________>   181  161 SET DISTANCE_RSR_MODEL = 7 
 
TOP_________>   182  162 SET MAXIMAL_DISTANCE = 7.0 
 
TOP_________>   183  163 SET ADD_RESTRAINTS = ON 
 
TOP_________>   184  164 SET RESTRAINT_GROUP = 27 
 
TOP_________>   185  165 SET RESTRAINT_STDEV = 0.2 0.0 
 
TOP_________>   186  166 SET RESIDUE_SPAN_RANGE = 0 99999, RESIDUE_SPAN_SIGN = OFF 
 
TOP_________>   187  167 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'ALL', RES_TY;
                      PES = 'ALL' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : ALL
Residue types to be searched for (RES_TYPES)   : ALL
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      880


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   188  168 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'ALL', RES_TY;
                      PES = 'HET' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : ALL
Residue types to be searched for (RES_TYPES)   : HET
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :        0


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN


TOP_________>   189  169 MAKE_RESTRAINTS 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     9158     9158
make_re_423_> Number of previous, current selected restraints:     9041     9041
TOP_________>   190  170 RETURN 
 
TOP_________>   191  152 CALL ROUTINE = 'blk_restraints' 
 
TOP_________>   192  173 SET RESTRAINT_TYPE = 'distance' 
 
TOP_________>   193  174 SET DISTANCE_RSR_MODEL = 7 
 
TOP_________>   194  175 SET MAXIMAL_DISTANCE = 10.0 
 
TOP_________>   195  176 SET ADD_RESTRAINTS = ON 
 
TOP_________>   196  177 SET RESTRAINT_GROUP = 27 
 
TOP_________>   197  178 SET RESTRAINT_STDEV = 0.05 0.0 
 
TOP_________>   198  179 SET RESIDUE_SPAN_RANGE = 0 0, RESIDUE_SPAN_SIGN = ON 
 
TOP_________>   199  180 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'ALL',  RES_T;
                      YPES = 'BLK' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : ALL
Residue types to be searched for (RES_TYPES)   : BLK
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :        0


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN


TOP_________>   200  181 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'ALL',  RES_T;
                      YPES = 'BLK' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : ALL
Residue types to be searched for (RES_TYPES)   : BLK
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :        0


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN


TOP_________>   201  182 MAKE_RESTRAINTS 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     9158     9158
make_re_423_> Number of previous, current selected restraints:     9041     9041
TOP_________>   202  183 SET RESTRAINT_STDEV = 0.2 0.0 
 
TOP_________>   203  184 SET RESIDUE_SPAN_RANGE = 1 99999, RESIDUE_SPAN_SIGN = OFF 
 
TOP_________>   204  185 PICK_ATOMS PICK_ATOMS_SET = 2, ATOM_TYPES = 'CA',  RES_TY;
                      PES = 'ALL' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : CA
Residue types to be searched for (RES_TYPES)   : ALL
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      108


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   205  186 PICK_ATOMS PICK_ATOMS_SET = 3, ATOM_TYPES = 'ALL', RES_TY;
                      PES = 'BLK' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : ALL
Residue types to be searched for (RES_TYPES)   : BLK
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): INITIALIZE
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :        0


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN


TOP_________>   206  187 MAKE_RESTRAINTS 
 

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8280957    8086.872     7.897
make_re_417_> Restraint type to be calculated:  distance
make_re_422_> Number of previous, current restraints         :     9158     9158
make_re_423_> Number of previous, current selected restraints:     9041     9041
TOP_________>   207  188 DELETE_ALIGNMENT 
 
TOP_________>   208  189 RETURN 
 

Dynamically allocated memory at         amaxseq [B,kB,MB]:      8171425    7979.907     7.793
TOP_________>   209  153 CALL ROUTINE = 'special_restraints' 
 
TOP_________>   210  498 RETURN 
 
TOP_________>   211  154 CONDENSE_RESTRAINTS 
 
delete__443_> Restraints marked for deletion were removed.
              Total number of restraints before, now:     9158     8362
TOP_________>   212  155 WRITE_RESTRAINTS FILE = CSRFILE 
 
openf5__224_> Open       14  UNKNOWN  SEQUENTIAL  sec1.rsr
TOP_________>   213  156 SET RESIDUE_SPAN_RANGE = -999 -999, RESIDUE_SPAN_SIGN = O;
                      N 
 
TOP_________>   214  157 RETURN 
 
TOP_________>   215  112 LABEL __SKIP_RSRS 
 
TOP_________>   216  113 RETURN 
 
TOP_________>   217  401 IF ARGUMENTS = EXIT_STAGE 1, OPERATION = 'GE', THEN = 'RE;
                      TURN' 
 
TOP_________>   218  402 CALL ROUTINE = 'rd_restraints' 
 
TOP_________>   219  255 READ_RESTRAINTS FILE = CSRFILE, ADD_RESTRAINTS = 'off' 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.rsr
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.rsr
rdcsr2__307_> Number of restraints read    :        0
              Number of excluded pairs read:        0
              Number of pseudo atoms read  :        0

Dynamically allocated memory at        amprmcns [B,kB,MB]:      8171425    7979.907     7.793
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.rsr
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.rsr
rdcsr2__307_> Number of restraints read    :        0
              Number of excluded pairs read:        0
              Number of pseudo atoms read  :        0
rdcsrs__304_> Restraints in memory, selected restraints:     8362     8362
              Explicitly excluded atom pairs in memory :        0
              Pseudo atoms in memory                   :        0
TOP_________>   220  256 RETURN 
 
TOP_________>   221  403 CALL ROUTINE = 'multiple_models' 
 
TOP_________>   222  192 DO ID2 = STARTING_MODEL  ENDING_MODEL  1 
 
TOP_________>   223  193 SET  FINAL_MODEL = 'default' 
 
TOP_________>   224  194 CALL ROUTINE     = 'single_model' 
 
TOP_________>   225  205 SET MAX_ITERATIONS = MAX_VAR_ITERATIONS 
 
TOP_________>   226  206 SET ID1 = 0 
 
TOP_________>   227  207 SWITCH_TRACE FILE = 'default', FILE_EXT = '', FILE_ID = ';
                      .D' 
 
openf5__224_> Open       18  UNKNOWN  SEQUENTIAL  sec1.D00000001
TOP_________>   228  208 READ_MODEL FILE = MODEL 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.ini
openf5__224_> Open       11  OLD  SEQUENTIAL  sec1.ini
rdatm___297_> Segments, residues, atoms:        1      108      880
rdatm___298_> Segment:        1     1     1      880
iatmcls_286W> MODEL atom not classified:  ASN:OT1  ASN
iatmcls_286W> MODEL atom not classified:  ASN:OT2  ASN
TOP_________>   229  209 CALL ROUTINE = 'select_atoms' 
 
TOP_________>   230  267 PICK_ATOMS SELECTION_SEGMENT ='@:@' 'X:X', SELECTION_SEAR;
                      CH ='segment',             PICK_ATOMS_SET =1, RES_TYPES =;
                      'all', ATOM_TYPES ='all',              SELECTION_FROM ='a;
                      ll', SELECTION_STATUS ='initialize' 
 

Number of atoms to choose from, total          :    880   880
Atom types to be searched for (ATOM_TYPES)     : all
Residue types to be searched for (RES_TYPES)   : all
Selection mode (SELECTION_MODE)                : ATOM
What to do with atoms & sets (SELECTION_STATUS): initialize
SEGMENT search; residue range (2i5,2a5)        :      1   108     1:    108:  
selatm__462_> Number of selected atoms            :      880


List of segments of contiguous residues with at least one selected atom: 

SEGMENT  RESNUM   AA ---  RESNUM   AA    LEN
      1    1 :  LYS  ---  108 :  ASN     108


TOP_________>   231  268 RETURN 
 
TOP_________>   232  210 CALL ROUTINE = RAND_METHOD 
 
TOP_________>   233  251 RANDOMIZE_XYZ 
 
randomi_498_> Atoms,selected atoms,random_seed,amplitude:      880      880        1        4.0000
randomi_496_> Amplitude is > 0; randomization is done.
TOP_________>   234  252 RETURN 
 
TOP_________>   235  211 MAKE_SCHEDULE 
 
openf5__224_> Open       11  OLD  SEQUENTIAL  ${MODINSTALL6v2}/modlib/sched.lib
TOP_________>   236  212 WRITE_SCHEDULE FILE = SCHFILE 
 
openf5__224_> Open       14  UNKNOWN  SEQUENTIAL  sec1.sch
TOP_________>   237  213 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                           THEN = 'WRITE_MODEL FILE = default, FILE_EXT = PDB_E;
                      XT', FILE_ID = '.B' 
 
TOP_________>   238  214 DO  IREPEAT = 1  REPEAT_OPTIMIZATION  1 
 
TOP_________>   239  215 CALL ROUTINE = 'single_model_pass' 
 
TOP_________>   240  231 DO SCHEDULE_STEP = 1  N_SCHEDULE  1 
 
TOP_________>   241  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   242  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     6147
TOP_________>   243  234 OPTIMIZE 
 

Dynamically allocated memory at         ampairs [B,kB,MB]:      8301657    8107.087     7.917
TOP_________>   244  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   245  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   246  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   247  238 END_DO 
 
TOP_________>   248  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   249  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     6814
TOP_________>   250  234 OPTIMIZE 
 
TOP_________>   251  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   252  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   253  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   254  238 END_DO 
 
TOP_________>   255  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   256  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     7223
TOP_________>   257  234 OPTIMIZE 
 
TOP_________>   258  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   259  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   260  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   261  238 END_DO 
 
TOP_________>   262  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   263  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     7508
TOP_________>   264  234 OPTIMIZE 
 
TOP_________>   265  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   266  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   267  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   268  238 END_DO 
 
TOP_________>   269  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   270  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     7763
TOP_________>   271  234 OPTIMIZE 
 
TOP_________>   272  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   273  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   274  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   275  238 END_DO 
 
TOP_________>   276  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   277  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     7983
TOP_________>   278  234 OPTIMIZE 
 
TOP_________>   279  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   280  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   281  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   282  238 END_DO 
 
TOP_________>   283  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   284  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     8137
TOP_________>   285  234 OPTIMIZE 
 
TOP_________>   286  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   287  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   288  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   289  238 END_DO 
 
TOP_________>   290  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   291  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     8351
TOP_________>   292  234 OPTIMIZE 
 
TOP_________>   293  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   294  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   295  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   296  238 END_DO 
 
TOP_________>   297  232 OPERATE ARGUMENTS = ID1 1, OPERATION = 'SUM', RESULT = ID;
                      1 
 
TOP_________>   298  233 PICK_RESTRAINTS ADD_RESTRAINTS = OFF 
 
pick_re_612_> Number of MODEL atoms, selected restraints;      880     8362
TOP_________>   299  234 OPTIMIZE 
 
TOP_________>   300  235 IF ARGUMENTS = WRITE_INTERMEDIATES 1, OPERATION = 'EQ',  ;
                               THEN = 'WRITE_MODEL FILE = default, FILE_EXT = P;
                      DB_EXT, FILE_ID = .B' 
 
TOP_________>   301  236 IF ARGUMENTS = ERROR_STATUS 0, OPERATION = 'GT',         ;
                       THEN = 'GO_TO __ABORT' 
 
TOP_________>   302  237 IF ARGUMENTS = MOLPDF MAX_MOLPDF, OPERATION = 'GT',      ;
                          THEN = 'GO_TO __ABORT' 
 
TOP_________>   303  238 END_DO 
 
TOP_________>   304  239 CALL ROUTINE = 'refine', SCHEDULE_STEP = N_SCHEDULE 
 
TOP_________>   305  271 STRING_IF STRING_ARGUMENTS = MD_LEVEL 'none', OPERATION =;
                       'EQ', THEN =      RETURN 
 
TOP_________>   306  272 STRING_IF STRING_ARGUMENTS = FIT_IN_REFINE 'NO_FIT', OPER;
                      ATION = 'NE',      THEN = 'WRITE_MODEL FILE = TO_BE_REFIN;
                      ED.TMP' 
 
TOP_________>   307  273 SET MAX_ITERATIONS_STORE = MAX_ITERATIONS 
 
TOP_________>   308  274 IF ARGUMENTS = REFINE_HOT_ONLY 1, OPERATION = 'NE', THEN ;
                         'GO_TO __BEGIN_MD' 
 
TOP_________>   309  285 CALL ROUTINE = MD_LEVEL 
 
TOP_________>   310  310 SET UPDATE_DYNAMIC = 0.39 
 
TOP_________>   311  311 SET CAP_ATOM_SHIFT = UPDATE_DYNAMIC, MD_TIME_STEP = 4.0 
 
TOP_________>   312  312 SET MAX_ITERATIONS = 50, EQUILIBRATE = 10, OPTIMIZATION_M;
                      ETHOD = 3 
 
TOP_________>   313  313 OPTIMIZE TEMPERATURE = 150.0, MD_RETURN = 'FINAL', INIT_V;
                      ELOCITIES = ON 
 
TOP_________>   314  314 OPTIMIZE TEMPERATURE = 400.0, MD_RETURN = 'FINAL', INIT_V;
                      ELOCITIES = OFF 
 
TOP_________>   315  315 OPTIMIZE TEMPERATURE =1000.0, MD_RETURN = 'FINAL' 
 
TOP_________>   316  316 SET EQUILIBRATE = 100, MAX_ITERATIONS = 300 
 
TOP_________>   317  317 OPTIMIZE TEMPERATURE =1000.0, MD_RETURN = 'FINAL' 
 
TOP_________>   318  318 OPTIMIZE TEMPERATURE = 800.0, MD_RETURN = 'FINAL' 
 
TOP_________>   319  319 OPTIMIZE TEMPERATURE = 500.0, MD_RETURN = 'FINAL' 
 
TOP_________>   320  320 OPTIMIZE TEMPERATURE = 300.0, MD_RETURN = 'FINAL' 
 
TOP_________>   321  321 RETURN 
 
TOP_________>   322  286 IF ARGUMENTS = REFINE_HOT_ONLY 1, OPERATION = 'NE', THEN ;
                         'GO_TO __AFTER_MD' 
 
TOP_________>   323  291 OPTIMIZE OPTIMIZATION_METHOD = 1, MAX_ITERATIONS = 200 
 
TOP_________>   324  292 STRING_IF STRING_ARGUMENTS = FIT_IN_REFINE 'NO_FIT', OPER;
                      ATION = 'INDEX',      THEN = 'GO_TO __NO_FIT' 
 
TOP_________>   325  306 SET MAX_ITERATIONS  = MAX_ITERATIONS_STORE 
 
TOP_________>   326  307 RETURN 
 
TOP_________>   327  240 LABEL __ABORT 
 
TOP_________>   328  241 SET ERROR_STATUS = 0 
 
TOP_________>   329  242 RETURN 
 
TOP_________>   330  216 END_DO 
 
TOP_________>   331  217 IUPAC_MODEL 
 
iupac_m_487_> NH1/2 swapped:      177.9643       11    11
iupac_m_487_> NH1/2 swapped:      175.3387       12    12
iupac_m_486_> OE1/2 swapped:     -135.8989       15    15
iupac_m_487_> NH1/2 swapped:      176.8704       24    24
iupac_m_483_> CD1/2 CE1/2 swapped:      112.8727       31    31
iupac_m_487_> NH1/2 swapped:     -177.5065       44    44
iupac_m_485_> OD1/2 swapped:     -174.8288       80    80
TOP_________>   332  218 SET ID1 = 9999 
 
TOP_________>   333  219 SET OUTPUT2 = OUTPUT 
 
TOP_________>   334  220 ENERGY OUTPUT = 'LONG VIOLATIONS_PROFILE', FILE = 'defaul;
                      t', FILE_ID = '.V', FILE_EXT = '' 
 


>> ENERGY; Differences between the model's features and restraints:


ID1, ID2                                          :     9999       1
Number of all residues in MODEL                   :      108
Number of all, selected real atoms                :      880     880
Number of all, selected pseudo atoms              :        0       0
Number of all static, selected restraints         :     8362    8362
COVALENT_CYS                                      :        F
NONBONDED_SEL_ATOMS                               :        1
Number of non-bonded pairs (excluding 1-2,1-3,1-4):     1470
Dynamic pairs routine                             : 2, NATM x NATM cell sorting
Atomic shift for contacts update (UPDATE_DYNAMIC) :    0.390
LENNARD_JONES_SWITCH                              :    6.500   7.500
COULOMB_JONES_SWITCH                              :    6.500   7.500
RESIDUE_SPAN_RANGE                                :        0     120
NLOGN_USE                                         :       15
CONTACT_SHELL                                     :    4.000
DYNAMIC_PAIRS,_SPHERE,_COULOMB,_LENNARD,_MODELLER :        T       T       F       F       F
SCHEDULE_STEP, N_SCHEDULE                         :        9       9
SPHERE_STDV                                       :    0.050
RADII_FACTOR                                      :    0.820
Current energy                                    :         658.5682
Symmetry term within energy                       :           0.0000





Summary of the restraint violations: 

   NUM     ... number of restraints.
   NUMVI   ... number of restraints with RVIOL > VIOL_REPORT_CUT[i].
   RVIOL   ... relative difference from the best value.
   NUMVP   ... number of restraints with -Ln(pdf) > VIOL_REPORT_CUT2[i].
   RMS_1   ... RMS(feature, minimally_violated_basis_restraint, NUMB).
   RMS_2   ... RMS(feature, best_value, NUMB).
   MOL.PDF ... scaled contribution to -Ln(Molecular pdf).

 #                     RESTRAINT_GROUP      NUM   NUMVI  NUMVP   RMS_1   RMS_2         MOL.PDF     S_i
------------------------------------------------------------------------------------------------------
 1 Bond length potential              :     911       0      0   0.004   0.004      4.7334       1.000
 2 Bond angle potential               :    1251       0      0   2.016   2.016      96.283       1.000
 3 Stereochemical cosine torsion poten:     676       0     20  46.641  46.641      213.87       1.000
 4 Stereochemical improper torsion pot:     387       0      0   1.113   1.113      10.430       1.000
 5 Soft-sphere overlap restraints     :    1470       0      0   0.002   0.002     0.55332       1.000
 6 Lennard-Jones 6-12 potential       :       0       0      0   0.000   0.000     0.00000       1.000
 7 Coulomb point-point electrostatic p:       0       0      0   0.000   0.000     0.00000       1.000
 8 H-bonding potential                :       0       0      0   0.000   0.000     0.00000       1.000
 9 Distance restraints 1 (CA-CA)      :     928       0      1   0.252   0.252      44.439       1.000
10 Distance restraints 2 (N-O)        :    1110       0      1   0.284   0.284      68.056       1.000
11 Mainchain Phi dihedral restraints  :       0       0      0   0.000   0.000     0.00000       1.000
12 Mainchain Psi dihedral restraints  :       0       0      0   0.000   0.000     0.00000       1.000
13 Mainchain Omega dihedral restraints:     107       0      0   3.537   3.537      14.948       1.000
14 Sidechain Chi_1 dihedral restraints:      94       0      0  58.670  58.670      14.422       1.000
15 Sidechain Chi_2 dihedral restraints:      72       0      0  63.006  63.006      22.940       1.000
16 Sidechain Chi_3 dihedral restraints:      31       0      0  42.911  42.911      15.224       1.000
17 Sidechain Chi_4 dihedral restraints:      10       0      0  80.110  80.110      7.6834       1.000
18 Disulfide distance restraints      :       0       0      0   0.000   0.000     0.00000       1.000
19 Disulfide angle restraints         :       0       0      0   0.000   0.000     0.00000       1.000
20 Disulfide dihedral angle restraints:       0       0      0   0.000   0.000     0.00000       1.000
21 Lower bound distance restraints    :       0       0      0   0.000   0.000     0.00000       1.000
22 Upper bound distance restraints    :       0       0      0   0.000   0.000     0.00000       1.000
23 Distance restraints 3 (SDCH-MNCH)  :    2046       0      0   0.469   0.469      74.586       1.000
24 Sidechain Chi_5 dihedral restraints:       0       0      0   0.000   0.000     0.00000       1.000
25 Phi/Psi pair of dihedral restraints:     106       5      5  29.326  43.894      18.548       1.000
26 Distance restraints 4 (SDCH-SDCH)  :     633       0      0   0.794   0.794      51.850       1.000
27 Distance restraints 5 (X-Y)        :       0       0      0   0.000   0.000     0.00000       1.000
28 NMR distance restraints 6 (X-Y)    :       0       0      0   0.000   0.000     0.00000       1.000
29 NMR distance restraints 7 (X-Y)    :       0       0      0   0.000   0.000     0.00000       1.000
30 Minimal distance restraints        :       0       0      0   0.000   0.000     0.00000       1.000
31 Non-bonded restraints              :       0       0      0   0.000   0.000     0.00000       1.000
32 Atomic accessibility restraints    :       0       0      0   0.000   0.000     0.00000       1.000
33 Atomic density restraints          :       0       0      0   0.000   0.000     0.00000       1.000



openf5__224_> Open       17  UNKNOWN  SEQUENTIAL  sec1.V99990001
# Heavy relative violation of each residue is written to: sec1.V99990001
# The profile is NOT normalized by the number of restraints.
# The profiles are smoothed over a window of residues:    1



List of the violated restraints:
   A restraint is violated when the relative difference
   from the best value (RVIOL) is larger than CUTOFF.

   ICSR   ... index of a restraint in the current set.
   RESNO  ... residue numbers of the first two atoms.
   ATM    ... IUPAC atom names of the first two atoms.
   FEAT   ... the value of the feature in the model.
   restr  ... the mean of the basis restraint with the smallest
              difference from the model (local minimum).
   viol   ... difference from the local minimum.
   rviol  ... relative difference from the local minimum.
   RESTR  ... the best value (global minimum).
   VIOL   ... difference from the best value.
   RVIOL  ... relative difference from the best value.


-------------------------------------------------------------------------------------------------

Feature 25                           : Phi/Psi pair of dihedral restraints     
List of the RVIOL violations larger than   :       6.5000

    #   ICSR  RESNO1/2 ATM1/2   INDATM1/2    FEAT   restr    viol   rviol   RESTR    VIOL   RVIOL
    1   3254  29P  30P C   N     234  236  -53.69  -58.70    8.97    0.54  -64.50  175.19   13.65
    1         30P  30P N   CA    236  237  -37.94  -30.50                  147.20
    2   3320  95A  96P C   N     773  775  -69.26  -58.70   11.40    1.60  -64.50  178.05   13.04
    2         96P  96P N   CA    775  776  -34.81  -30.50                  147.20
    3   3321  96P  97I C   N     780  782   49.60  -97.30  147.36    6.38 -120.60  170.84   11.37
    3         97I  97I N   CA    782  783  115.64  127.20                  130.30
    4   3324  99T 100N C   N     807  809  -99.19  -63.20   75.76   11.49  -63.20   75.76   11.49
    4        100N 100N N   CA    809  810 -107.76  -41.10                  -41.10
    5   3330 105I 106T C   N     856  858  -54.70  -63.20   19.84    2.12  -78.10  151.98    7.29
    5        106T 106T N   CA    858  859  -60.03  -42.10                  149.80


report______> Distribution of short non-bonded contacts:


DISTANCE1:  0.00 2.10 2.20 2.30 2.40 2.50 2.60 2.70 2.80 2.90 3.00 3.10 3.20 3.30 3.40
DISTANCE2:  2.10 2.20 2.30 2.40 2.50 2.60 2.70 2.80 2.90 3.00 3.10 3.20 3.30 3.40 3.50
FREQUENCY:     0    0    0    0    0    6   13   27   61   56   84   84  102  111  111



<< end of ENERGY.
TOP_________>   335  221 SET OUTPUT = OUTPUT2 
 
TOP_________>   336  222 CALL ROUTINE = 'user_after_single_model' 
 
TOP_________>   337  228 RETURN 
 
TOP_________>   338  223 WRITE_MODEL FILE = FINAL_MODEL, FILE_ID = '.B', FILE_EXT ;
                      = PDB_EXT 
 
openf5__224_> Open       14  UNKNOWN  SEQUENTIAL  sec1.B99990001
wrpdb2__568_> Residues, atoms, selected atoms:      108      880      880
TOP_________>   339  224 SET FINAL_MODEL = FILE 
 
TOP_________>   340  225 RETURN 
 
TOP_________>   341  195 END_DO 
 
TOP_________>   342  196 IF ARGUMENTS = DO_LOOPS 1, OPERATION = 'NE', THEN = 'GO_T;
                      O NO_LOOPS' 
 
TOP_________>   343  202 RETURN 
 
TOP_________>   344  404 IF ARGUMENTS =FINAL_MALIGN3D 1, OPERATION ='NE', THEN ='G;
                      O_TO NO_MALIGN3D' 
 
TOP_________>   345  411 RETURN 
 

Dynamically allocated memory at          finish [B,kB,MB]:      8301657    8107.087     7.917
Starting time                                            : 2003/04/23  11:48:58.409
Closing time                                             : 2003/04/23  11:49:53.150
Total CPU time [seconds]                                 :      54.51