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leaving gaps in non aligned regions
- To: modeller_usage@listsrv.ucsf.edu
- Subject: leaving gaps in non aligned regions
- From: Gowthaman R <gowtham AT icgeb.res.in>
- Date: Fri, 13 Dec 2002 01:19:46 +0530 (GMT+5:30)
- Cc: Bozidar Yerkovich <bozidar AT salilab.org>
hello modellers,
i am trying to model some proteins. but my protein has some region
(internal) (15-20 amino acids) which does not have any corresponding
region in the template sequence.
i DO NOT want to model that region and in my final (3D) strucuture i
want to have a gap in the corresponding internal region. other wise that
region
forms a loop or extended region ( makes the structre ugly ??).
i wish to know how my alignement file should look like....
i tried following and did not solve the problem
1) putting " X " for the amino acids for which i dont want the 3D
structure to be made
2) puting " - " for the same...
waiting for ur reply
gowthaman
Phd Student
ICGEB,
India.